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Machine Learning + Bioinformatics Positions Available



Apologies if you receive more than one copy of this announcement.

2 Research Fellowships, 1 Ph.D. Scholarship Available

We are pleased to announce the availability the following Bioinformatics 
/ Computational biology positions in the School of Computer Science & IT 
at the University of Nottingham under the supervision of Dr. N. Krasnogor:

Project “Robust Prediction with Explanatory Power for Protein Structure 
and Related Prediction Problems”

·	1 funded Ph.D. Scholarship (3 years funding)
·	1 Postdoctoral research fellowship (3 years project)

Project “Automated, Grid-Aware, Three-Tier Protocol for Protein 
Structure Comparison”

·	1 Postdoctoral research fellowship (1.5 years project)

Robust Prediction with Explanatory Power for Protein Structure and 
Related Prediction Problems
-----------------------------------

The “Robust Prediction with Explanatory Power for Protein Structure and 
Related Prediction Problems.” is a collaborative project with The 
University of the West of England and The School of Chemistry at the 
University of Nottingham.

The project intends to develop more general, intelligent and reliable 
classification and predictive technologies for problems in 
bioinformatics (particularly, predicting the structure of proteins). We 
aim to explore and investigate the feasibility of designing and 
implementing robust classification and predictive systems that can 
deliver high quality predictions at the same time as 
human-understandable explanations for those predictions. A successful 
outcome to this project could lead to a greater understanding of the 
issues that underpin predictive and classification software systems in 
general, and perhaps more importantly, those that have an immediate 
impact on quality of human life: bioinformatics. It is in domains like 
this where the availability of human-understandable explanations are as 
important as correct predictions. In this project, we will employ a 
variety of machine learning technology. We expect that the new machine 
learning techniques that we will develop would yield robust, accurate 
predictions, with the explanatory power not available in other methods.

The ideal candidate will have an existing understanding of machine 
learning, particularly evolutionary computation and neural networks. 
However, candidates with other relevant experience may be considered.

The Ph.D. vacancy is open only to UK and EU students. They should have 
at least an upper second-class honours degree (ideally a first class 
degree), or a combination of qualifications and/or experience equivalent 
to that level. Candidate Ph.D. students must apply with a cover letter 
explaining why they want to pursue doctoral studies, a list of 
publications (if available), two references and a CV. ALL THE MATERIAL 
MUST BE SENT IN PDF.

The Postdoctoral vacancy is open to any person with suitable 
qualifications. As a minimum she/he must have a Ph.D. in computer 
sciences, mathematics, physics, chemistry or biology. If the Ph.D. is 
not in computer science then proven programming skills are a required 
condition. Relevant experience in Bioinformatics/Computational Biology 
is a plus. Candidate Postdocs must apply with a cover letter mentioning 
past and current research interests, list of publications, copy of 
her/his top two publications, detailed CV and three references. ALL THE 
MATERIAL MUST BE SENT IN PDF.

It is expected that the Ph.D. scholarship and Postdoctoral fellowship 
would begin early 2005.

Application Deadline is 25 December 2004.

The Postdoctoral salary will be within the range £18,893 - £24,097 per 
annum, depending on qualifications and experience.  This EPSRC funded 
post is available from 1 February 2005 and will be offered on a 
fixed-term contract for a period of three years.
The Ph.D. scholarship covers home fees + a stipend (which for 2005/06 is 
12,000 pounds).

For further information or for applications, please email 
Natalio.Krasnogor@Nottingham.ac.uk, in the subject mention the title of 
the project and the position you are interested in. If applying please 
attach the PDF files with the requested material.


Automated, Grid-Aware, Three-Tier Protocol for Protein Structure Comparison
-----------------------------

The “Automated, Grid-Aware, Three-Tier Protocol for Protein Structure 
Comparison” is a collaborative project with The School of Chemistry at 
the University of Nottingham.

The comparison of protein structures, and their clustering (according to 
similarity) is a fundamental aspect of today's biomedical research.  The 
comparison of the 3D structures of protein molecules is a challenging 
problem. The search for effective solution techniques for this problem 
is justified because such tools can aid scientists in the development of 
procedures for drug design, in the identification of new types of 
protein architecture, in the organization of the known universe of 
protein structures and can help to discover unexpected evolutionary and 
functional inter-relations between proteins. There is yet another 
important role for measures of similarity and clustering algorithms: the 
evaluation of ab initio, threading or homology modelling structure 
predictions.  Hence, any advancement in structural similarity measures 
will also impact  on structure prediction and  the methodologies for the 
evaluation of those predictions .  In this projectl we will undertake 
the implementation of an extended (three-tier) protocol for protein 
structure comparison  building on our recent research progress.

The Postdoctoral vacancy is open to any person with suitable 
qualifications. As a minimum he/she must have a Ph.D. in computer 
sciences, mathematics, physics, chemistry or biology. If the Ph.D. is 
not in computer science then excellent proven programming skills are a 
required condition. Relevant experience in Bioinformatics/Computational 
Biology is a plus, particularly the implementation of public 
web-services or GRID based architectures.
Candidates must apply with a cover letter mentioning past and current 
research interests, list of publications, copy of her/his top two 
publications, detailed CV and three references. ALL THE MATERIAL MUST BE 
SENT IN PDF.

It is expected that Postdoctoral fellowship would begin in early 2005.
Application Deadline is 15 December 2004.

Salary will be within the range £18,893 - £24,097 per annum, depending 
on qualifications and experience.  This BBSRC funded post is available 
from 1 January 2005 and will be offered on a fixed-term contract for a 
period of one and a half years.

For further information or for applications, please email 
Natalio.Krasnogor@Nottingham.ac.uk, in the subject mention the title of 
the project and the position you are interested in. If applying please 
attach the PDF files with the requested material.

-- 

PS1: Please check out the call for chapter contributions to the book 
"Systems Self-Assembly: Multidisciplinary Snapshots"
http://www.cs.nott.ac.uk/~nxk/SYSEAS/index.html

PS2: Please check out our new book "Recent Advances in Memetic Algorithms"
www.springeronline.com/sgw/cda/frontpage/0,11855,5-40356-72-34233226-0,00.html
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NATALIO KRASNOGOR, Ph.D.    Automated Scheduling, Planning and 
Optimisation  Group
Lecturer                    School of Computer Sciences and Information 
Technology
                             Jubilee Campus
                             University of Nottingham 

Tel.: +44 - 0115 - 8467592  Nottingham, NG81BB
                             United Kingdom

URL: http://www.cs.nott.ac.uk/~nxk/

e-mail: Natalio.Krasnogor-replace all this by at symbol-nottingham.ac.uk
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We have recently published a book on Fuzzy Sets, details at
http://www.springer-ny.com/detail.tpl?isbn=354000551X